Ester and peptide synthesis by proteases in organic solvents.

synthesis of 3-aryl-2h-benzo[b]-1,4-oxazines in [omim]bf4 and reduction of organic compounds in methylimidazolium formate

در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...

DNA-templated synthesis in organic solvents.

DNA-templated organic synthesis (DTS) enables new modes of controlling chemical reactivity and allows evolutionary principles to be applied to the discovery of synthetic small molecules, synthetic polymers, and new chemical reactions. The structures that can be accessed in a DNA-templated format thus far have been limited to those that can be generated in aqueous solvents. Here we report effici...

Solvents for solid-phase peptide synthesis.

Modification Effects of Organic Solvents on Microenvironment of the Enzyme in Thermolysin - catalyzed Peptide Synthesis of N - ( Benzyloxycarbonyl ) - L - phenylalanyl - L - phenylalanine Methyl Ester

L-phenyta}anine methy] ester (Phe-OMe) as substrates was dene mainly in a water-organic one phase solvent system. The organic so]yent content used was less than the saturatien concentration in buffer. With organic solvents with high logP ya]ues, the enzymatic actiyity increased as the organic solyent content increased; but further increases in the organic solvent content decreased the enzymatic...

The Solvent Selection framework: solvents for organic synthesis, separation processes and ionic-organic synthesis

This paper presents a systematic integrated framework for solvent selection and solvent design. The framework is divided into several modules, which can tackle specific problems in various solvent-based applications. In particular, three modules corresponding to the following solvent selection problems are presented: 1) solvent selection and design for organic synthesis, 2) solvent screening an...